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Mar 9, 2010 SOURCE: Clinical Rheumatology |
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Retrospective clinical study of the efficacy of lower-dose methotrexate and infliximab therapy in patients with rheumatoid arthritis |
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The objective of this study is to compare the long-term outcomes of infliximab therapy with lower-dose methotrexate (MTX;=4 mg per week) and with standard-dose MTX (>/=6 mg per week) in Japanese rheumatoid arthritis (RA) patients. One hundred thirty-eig |
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Mar 8, 2010 SOURCE: British Medical Bulletin |
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New understanding and approaches to treatment in rheumatoid arthritis |
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Rheumatoid arthritis (RA) is the most common autoimmune inflammatory polyarthritis. Significant advances in the understanding of its pathogenesis have led in the past two decades to major advancement in its therapy. We used data from articles in Cochrane |
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Mar 8, 2010 SOURCE: Neurosurgery |
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Rheumatoid arthritis of the craniovertebral junction |
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BACKGROUND: Rheumatoid arthritis (RA) is the most common inflammatory disease involving the spine. It has a predilection for involving the craniocervical spine. Despite widespread involvement of the cervical spine with RA, few patients need surgery. The 3 |
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Mar 4, 2010 SOURCE: DGNews |
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TopAbstracts in Rheumatoid Arthritis 03/04/2010 |
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TopAbstracts - Past 14 days
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Mar 4, 2010 SOURCE: Journal of Rheumatology |
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Efficacy and Safety of Retreatment in Patients with Rheumatoid Arthritis with Previous Inadequate Response to Tumor Necrosis Factor Inhibitors: Results from the SUNRISE Trial |
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OBJECTIVE: To assess the efficacy and safety of 1 versus 2 courses of rituximab over 48 weeks in patients with rheumatoid arthritis (RA). METHODS: Adult patients taking methotrexate with a previous inadequate response to>/= 1 tumor necrosis factor inhibit |
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Mar 4, 2010 SOURCE: Journal of Rheumatology |
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Associations Between Tumor Necrosis Factor-{alpha} (TNF-{alpha}) -308 and -238 G/A Polymorphisms and Shared Epitope Status and Responsiveness to TNF-{alpha} Blockers in Rheumatoid Arthritis: A Metaanalysis Update |
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OBJECTIVE: To investigate whether tumor necrosis factor-alpha (TNF-alpha) promoter -308 A/G and -238 A/G polymorphisms and shared epitope (SE) status are associated with responsiveness to anti-TNF therapy in patients with rheumatoid arthritis (RA). METHOD |
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Mar 4, 2010 SOURCE: Journal of Rheumatology |
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Multiplex Screening of 22 Single-Nucleotide Polymorphisms in 7 Toll-like Receptors: An Association Study in Rheumatoid Arthritis |
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OBJECTIVE: Toll-like receptors (TLR) have been implicated in the pathogenesis of arthritis. We investigated the role of functional variants of TLR in the disease phenotype and severity of rheumatoid arthritis (RA). METHODS: All patients from a longterm ob |
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Mar 4, 2010 SOURCE: Journal of Rheumatology |
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Comparison of the Construct Validity and Sensitivity to Change of the Visual Analog Scale and a Modified Rating Scale as Measures of Patient Global Assessment in Rheumatoid Arthritis |
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OBJECTIVE: Patient global assessment (PGA) is commonly measured using a visual analog scale (VAS). The VAS asks patients to integrate many dimensions of rheumatoid arthritis (RA) activity, yet its scope is poorly defined and its endpoints are vague. We in |
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Mar 4, 2010 SOURCE: Journal of Rheumatology |
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Clinical Activity After 12 Weeks of Treatment with Nonbiologics in Early Rheumatoid Arthritis May Predict Articular Destruction 2 Years Later |
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OBJECTIVE: To investigate earlier prediction of future articular destruction in patients with early rheumatoid arthritis (RA). METHODS: We randomly allocated patients with RA with disease duration<2 years to different nonbiologic disease modifying antirhe |
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Mar 3, 2010 SOURCE: Joint Bone Spine |
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Usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy or rheumatoid arthritis |
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OBJECTIVE: To assess the usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy (SpA) or rheumatoid arthritis (RA). METHODS: We included consecutive patients with SpA or RA or with degenerative joint dis |
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