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Rheumatoid Arthritis News

  Mar 9, 2010 – SOURCE: Clinical Rheumatology
Doctor's Guide News Retrospective clinical study of the efficacy of lower-dose methotrexate and infliximab therapy in patients with rheumatoid arthritis
The objective of this study is to compare the long-term outcomes of infliximab therapy with lower-dose methotrexate (MTX;/=6 mg per week) in Japanese rheumatoid arthritis (RA) patients. One hundred thirty-eig
 
  Mar 8, 2010 – SOURCE: British Medical Bulletin
Doctor's Guide News New understanding and approaches to treatment in rheumatoid arthritis
Rheumatoid arthritis (RA) is the most common autoimmune inflammatory polyarthritis. Significant advances in the understanding of its pathogenesis have led in the past two decades to major advancement in its therapy. We used data from articles in Cochrane
 
  Mar 8, 2010 – SOURCE: Neurosurgery
Doctor's Guide News Rheumatoid arthritis of the craniovertebral junction
BACKGROUND: Rheumatoid arthritis (RA) is the most common inflammatory disease involving the spine. It has a predilection for involving the craniocervical spine. Despite widespread involvement of the cervical spine with RA, few patients need surgery. The 3
 
  Mar 4, 2010 – SOURCE: DGNews
Doctor's Guide News TopAbstracts in Rheumatoid Arthritis 03/04/2010
TopAbstracts - Past 14 days

 
  Mar 4, 2010 – SOURCE: Journal of Rheumatology
Doctor's Guide News Efficacy and Safety of Retreatment in Patients with Rheumatoid Arthritis with Previous Inadequate Response to Tumor Necrosis Factor Inhibitors: Results from the SUNRISE Trial
OBJECTIVE: To assess the efficacy and safety of 1 versus 2 courses of rituximab over 48 weeks in patients with rheumatoid arthritis (RA). METHODS: Adult patients taking methotrexate with a previous inadequate response to>/= 1 tumor necrosis factor inhibit
 
  Mar 4, 2010 – SOURCE: Journal of Rheumatology
Doctor's Guide News Associations Between Tumor Necrosis Factor-{alpha} (TNF-{alpha}) -308 and -238 G/A Polymorphisms and Shared Epitope Status and Responsiveness to TNF-{alpha} Blockers in Rheumatoid Arthritis: A Metaanalysis Update
OBJECTIVE: To investigate whether tumor necrosis factor-alpha (TNF-alpha) promoter -308 A/G and -238 A/G polymorphisms and shared epitope (SE) status are associated with responsiveness to anti-TNF therapy in patients with rheumatoid arthritis (RA). METHOD
 
  Mar 4, 2010 – SOURCE: Journal of Rheumatology
Doctor's Guide News Multiplex Screening of 22 Single-Nucleotide Polymorphisms in 7 Toll-like Receptors: An Association Study in Rheumatoid Arthritis
OBJECTIVE: Toll-like receptors (TLR) have been implicated in the pathogenesis of arthritis. We investigated the role of functional variants of TLR in the disease phenotype and severity of rheumatoid arthritis (RA). METHODS: All patients from a longterm ob
 
  Mar 4, 2010 – SOURCE: Journal of Rheumatology
Doctor's Guide News Comparison of the Construct Validity and Sensitivity to Change of the Visual Analog Scale and a Modified Rating Scale as Measures of Patient Global Assessment in Rheumatoid Arthritis
OBJECTIVE: Patient global assessment (PGA) is commonly measured using a visual analog scale (VAS). The VAS asks patients to integrate many dimensions of rheumatoid arthritis (RA) activity, yet its scope is poorly defined and its endpoints are vague. We in
 
  Mar 4, 2010 – SOURCE: Journal of Rheumatology
Doctor's Guide News Clinical Activity After 12 Weeks of Treatment with Nonbiologics in Early Rheumatoid Arthritis May Predict Articular Destruction 2 Years Later
OBJECTIVE: To investigate earlier prediction of future articular destruction in patients with early rheumatoid arthritis (RA). METHODS: We randomly allocated patients with RA with disease duration<2 years to different nonbiologic disease modifying antirhe
 
  Mar 3, 2010 – SOURCE: Joint Bone Spine
Doctor's Guide News Usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy or rheumatoid arthritis
OBJECTIVE: To assess the usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy (SpA) or rheumatoid arthritis (RA). METHODS: We included consecutive patients with SpA or RA or with degenerative joint dis