Osteoporosis News
| Mar 9, 2010 – SOURCE: Journal of Women's Health | |||
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Are All Bisphosphonates the Same? Potential Reasons for Clinical Differences: A Perspective | |
| Abstract Bisphosphonates are first-line treatment for postmenopausal osteoporosis and women with low bone mass and risk factors for fracture. These agents are often perceived as having equivalent effectiveness and safety and are even used interchangeably | |||
| Mar 9, 2010 – SOURCE: Der Radiologe | |||
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Radiological diagnosis of osteoporosis | |
| Having at their disposal a wide range of imaging techniques, radiologists play a crucial role in the diagnostic evaluation of patients with osteoporosis. The radiological tests range from dual energy X-ray absorptiometry (DXA), which is the only reference | |||
| Mar 9, 2010 – SOURCE: Clinical Biomechanics (Bristol, Avon) | |||
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Does stride length influence metabolic cost and biomechanical risk factors for knee osteoarthritis in obese women? | |
| BACKGROUND: Obesity is the primary modifiable risk factor for knee osteoarthritis. The goal of this study was to develop a walking protocol for obese individuals that supported weight loss while minimizing biomechanical risk factors for knee osteoarthriti | |||
| Mar 9, 2010 – SOURCE: Canadian Association of Radiologists Journal | |||
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Combined Vertebral Fracture Assessment and Bone Mineral Density Measurement: A Patient-Friendly New Tool with an Important Impact on the Canadian Risk Fracture Classification | |
| PURPOSE: Vertebral fractures often go unnoticed, while they constitute a significant risk factor for new fractures, independent of the bone density. Vertebral Fracture Assessment (VFA) is a new feature on DXA bone densitometry equipment. Our purpose was t | |||
| Mar 8, 2010 – SOURCE: Osteoarthritis and Cartilage | |||
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Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study | |
| OBJECTIVE: To evaluate the efficacy and safety of the cyclooxygenase-inhibiting nitric-oxide donator, naproxcinod, compared with naproxen and placebo in patients with osteoarthritis (OA) of the knee. METHOD: 918 eligible patients were randomly assigned to | |||
| Mar 8, 2010 – SOURCE: Osteoporosis International | |||
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Depression, fracture risk, and bone loss: a meta-analysis of cohort studies | |
| Whether depression can increase the risk of bone fractures is uncertain. This meta-analysis, which pooled results from 14 qualifying individual cohort studies, found that depression was associated with a significantly increased risk of fractures and bone | |||
| Mar 8, 2010 – SOURCE: Osteoporosis International | |||
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Effect of calcium and vitamin D supplementation on bone mineral density in women aged 65-71 years: a 3-year randomized population-based trial (OSTPRE-FPS) | |
| The Osteoporosis Risk Factor and Prevention-Fracture Prevention Study (OSTPRE-FPS) was a randomized population-based open trial (n = 593). The supplementation group (n = 287) received daily cholecalciferol 800 IU + calcium 1,000 mg for 3 years while the c | |||
| Mar 8, 2010 – SOURCE: Clinical Rheumatology | |||
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Vitamin D status, dependence on age, and seasonal variations in the concentration of vitamin D in Croatian postmenopausal women initially screened for osteoporosis | |
| Vitamin D deficiency is associated with secondary hyperparathyroidism, increased bone turnover, and bone loss, leading to increased risk for osteoporotic fractures. The objective of this study was to investigate the prevalence of inadequate (insufficient | |||
| Mar 8, 2010 – SOURCE: Journal of Bone and Mineral Research | |||
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The Effect of Prior Bisphosphonate Therapy on the Subsequent BMD and Bone Turnover Response to Strontium Ranelate | |
| Introduction: Strontium ranelate is an effective treatment for osteoporosis in treatment nïve women. In the United Kingdom bisphosphonates are often used first line. Prior bisphosphonate use may blunt the BMD response to strontium ranelate by reducing st | |||
| Mar 8, 2010 – SOURCE: Journal of Bone and Mineral Research | |||
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Serum 25(OH)D Levels Modulate the Acute Phase Response Associated to the First Nitrogen Containing Bisphosphonate Infusion | |
| The acute phase response (APR) is the most frequent side-effect after the first dose of intravenous nitrogen-containing bisphosphonates (N-BPs). It has been demonstrated in vitro that N-BPs stimulate gammadeltaTcells proliferation and production of cytoki | |||
