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HIV News

  Jul 24, 2008 – SOURCE: HIV Medicine
Doctor's Guide News Effect of haematological alterations on thalassaemia investigation in HIV-1-infected Thai patients receiving antiretroviral therapy
Objectives To evaluate the effect of haematological alterations resulting from antiretroviral therapy (ART) on the diagnosis of thalassaemia carriers in HIV-1-infected Thai patients. Methods Complete blood cell counts, osmotic fragility (OF) test and haem
 
  Jul 24, 2008 – SOURCE: Journal of Acquired Immune Deficiency Syndromes
Doctor's Guide News Poor Initial CD4+ Recovery With Antiretroviral Therapy Prolongs Immune Depletion and Increases Risk for AIDS and Non-AIDS Diseases
BACKGROUND:: Low CD4+ increases risk for both AIDS- and non-AIDS-related morbidity and mortality. The magnitude of CD4+ recovery early after initial antiretroviral therapy (ART) is important in the ultimate duration of immune depletion. METHODS:: We exami
 
  Jul 24, 2008 – SOURCE: Journal of Acquired Immune Deficiency Syndromes
Doctor's Guide News Viral Dynamics and In Vivo Fitness of HIV-1 in the Presence and Absence of Enfuvirtide
OBJECTIVES:: To estimate the in vivo fitness cost of enfuvirtide (ENF) resistance, we analyzed dynamic shifts in the HIV-1 quasispecies under changing selective pressure in 3 subjects on failing ENF-based regimens who interrupted ENF while maintaining sta
 
  Jul 24, 2008 – SOURCE: DGNews
Doctor's Guide News Extended-Dose Nevirapine May Reduce Risk of Mother-to-Infant HIV Transmission in Developing Countries
NEW YORK -- July 24, 2008 -- A regimen of extended-dose nevirapine could reduce the risk of infants contracting the HIV virus from their HIV-infected mothers, according to a study in this week's HIV special issue of The Lancet.

A long co
 
  Jul 24, 2008 – SOURCE: DGNews
Doctor's Guide News FDA Recommends Genetic Screening Prior to Treatment With Abacavir
ROCKVILLE, Md -- July 24, 2008 -- The US Food and Drug Administration (FDA) has issued an alert regarding serious, and sometimes fatal, hypersensitivity reactions (HSRs) caused by abacavir (Ziagen) therapy in patients with a particular human leukocyte ant
 
  Jul 24, 2008 – SOURCE: DGNews
Doctor's Guide News Contaminated Nelfinavir Does Not Increase Cancer Risk, EMEA Concludes
LONDON -- July 24, 2008 -- Following a review of a number of toxicology studies, the European Medicines Agency (EMEA) confirms that there is no increased risk of developing cancer for patients who have taken nelfinavir (Viracept) contaminated with ethyl m
 
  Jul 24, 2008 – SOURCE: Journal of Acquired Immune Deficiency Syndromes
Doctor's Guide News Influence of Antiretroviral Drugs on the Pharmacokinetics of Prednisolone in HIV-Infected Individuals
BACKGROUND:: Corticosteroids are cytochrome P450 3A4 substrates, which have been associated with toxicities in patients receiving cytochrome P450 3A4 inhibitors such as human immunodeficiency virus protease inhibitors. In a study in healthy volunteers, ri
 
  Jul 24, 2008 – SOURCE: Clinical Gastroenterology and Hepatology
Doctor's Guide News Noncirrhotic Portal Hypertension in Patients With Human Immunodeficiency Virus-1 Infection
BACKGROUND&AIMS: Noncirrhotic portal hypertension (NCPH) is unusual in North American patients. This study characterized patients with NCPH and human immunodeficiency virus-1 (HIV-1) infection to identify potential risk factors for this association. METHO
 
  Jul 23, 2008 – SOURCE: Head & Neck
Doctor's Guide News Primary squamous cell carcinoma of Stensen's duct in a patient with HIV: The role of magnetic resonance imaging and fine-needle aspiration
BACKGROUND.: Primary malignant tumors involving Stensen's duct are rare neoplasms, with less than 30 cases reported. We report a case of primary squamous cell carcinoma (SCC) involving Stensen's duct in a patient infected with human immunodeficiency virus
 
  Jul 23, 2008 – SOURCE: Journal of the American Academy of Dermatology
Doctor's Guide News Disseminated Trichosporon inkin and Histoplasma capsulatum in a patient with newly diagnosed AIDS
Histoplasma capsulatum and Trichosporon inkin may cause disseminated disease in immunocompromised patients. Disseminated T inkin, the causative agent of white piedra, is rare and difficult to diagnose. We report the case of a 28 year-old man with newly di