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Hepatology News

  Jul 24, 2008 – SOURCE: Journal of Viral Hepatitis
Doctor's Guide News A continuous (13)C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT
Up to 30% of patients with hepatitis C virus (HCV) infection and normal serum alanine aminotransferase (NALT) have significant liver disease. Currently, many of these patients undergo a liver biopsy to guide therapeutic decisions. The BreathID((R)) contin
 
  Jul 24, 2008 – SOURCE: Journal of Hepatology
Doctor's Guide News Evaluation of complement factor 5 variants as genetic risk factors for the development of advanced fibrosis in chronic hepatitis C infection
BACKGROUND/AIMS: Intercross studies in inbred mice susceptible or resistant to liver fibrosis revealed complement factor 5 as a quantitative trait gene associated with the development of fibrosis. In 277 patients with hepatitis C, two C5 SNPs, rs17611 and
 
  Jul 24, 2008 – SOURCE: Journal of Surgical Oncology
Doctor's Guide News Response to interferon therapy affects risk factors for postoperative recurrence of hepatitis C virus-related hepatocellular carcinoma
BACKGROUND: Interferon therapy might reduce recurrence after resection of hepatitis C virus-related hepatocellular carcinoma, especially among sustained virologic or biochemical responders. METHODS: Of 209 patients who underwent curative resection for ear
 
  Jul 24, 2008 – SOURCE: Ophthalmic Plastic and Reconstructive Surgery (OPRS)
Doctor's Guide News Sarcoid-like Granulomatous Orbital Inflammation Induced by Interferon-alpha Treatment
A 56-year-old black woman presented with bilateral orbital swelling in the lacrimal gland region 4 months after initiation of interferon-alpha and ribavirin treatment for occupationally-acquired hepatitis C infection. Histopathologic evaluation of bilater
 
  Jul 24, 2008 – SOURCE: Archives of Surgery
Doctor's Guide News Liver transplant for hepatitis C virus: effect of using older donor grafts on short- and medium-term survival
HYPOTHESIS: Older donor grafts will provide suitable results of liver transplant, even in recipients with hepatitis C virus (HCV). Although HCV remains the leading indication for liver transplant in adults in the United States, it is associated with HCV r
 
  Jul 23, 2008 – SOURCE: Infection
Doctor's Guide News Therapeutical Aspects and Outcome of HIV/HCV Coinfected Patients Treated with Pegylated Interferon plus Ribavirin in an Italian Cohort
BACKGROUND: One-third of HIV-infected individuals suffer from chronic hepatitis C virus infection (HCV) in Europe. Recommendations from HCV-HIV International Panel advise current treatment with pegylated interferon plus ribavirin. We assessed the impact o
 
  Jul 22, 2008 – SOURCE: DGNews
Doctor's Guide News TopAbstracts in Hepatitis C 07/22/2008
TopAbstracts - Past 14 days

 
  Jul 22, 2008 – SOURCE: Journal of Viral Hepatitis
Doctor's Guide News Active intravenous drug use during chronic hepatitis C therapy does not reduce sustained virological response rates in adherent patients
Reluctance has been expressed about treating chronic hepatitis C in active intravenous (IV) drug users (IDUs), and this is found in both international guidelines and routine clinical practice. However, the medical literature provides no evidence for an un
 
  Jul 21, 2008 – SOURCE: DGNews
Doctor's Guide News Livers From Elderly Donors Safe, Effective for Recipients With Hepatitis C
CHICAGO -- July 21, 2008 -- Receiving a liver from a donor aged 60 years and older does not appear to be associated with transplant failure, death, or recurrent disease in the next 5 years among transplant recipients with hepatitis C, according to a study
 
  Jul 21, 2008 – SOURCE: Journal of Viral Hepatitis
Doctor's Guide News Correlation of serum ribavirin concentration with pretreatment renal function estimates in patients with chronic hepatitis C receiving combination antiviral therapy with peginterferon and ribavirin
Serum ribavirin concentration is an important factor in antiviral therapy in combination with peginterferon (PEG-IFN) and ribavirin for patients with chronic hepatitis C in terms of both beneficial and adverse effects. We evaluated whether the serum ribav