Hepatology News
| Mar 9, 2010 – SOURCE: European Journal of Cancer | |||
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Hepatitis B virus-associated intrahepatic cholangiocarcinoma and hepatocellular carcinoma may hold common disease process for carcinogenesis | |
| AIMS: To evaluate potential risk factors for intrahepatic cholangiocarcinoma (ICC) and analyse clinicopathologic characteristics of ICC patients with seropositive hepatitis B surface antigen (HBsAg). METHODS: A retrospective case-control study was conduct | |||
| Mar 9, 2010 – SOURCE: Clinical Hemorheology and Microcirculation | |||
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Alteration of serum thrombopoietin levels in patients with chronic hepatitis C under interferon therapy | |
| Thrombocytopenia is commonly observed during interferon-alpha (IFN-alpha) therapy in patients with chronic hepatitis C. Since thrombopoietin (TPO) is the main regulator of thrombopoiesis, thrombocytopenia may partially be due to a reduced TPO generation. | |||
| Mar 8, 2010 – SOURCE: Expert Opinion on Pharmacotherapy | |||
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Treatment of viral hepatitis B in children | |
| Importance of the field: Treatment of chronic hepatitis B (CHB) in children is aimed at reducing viral replication and at minimizing liver injury and related consequences in children with chronic active viral liver infection. Areas covered in this review: | |||
| Mar 8, 2010 – SOURCE: World Journal of Gastroenterology | |||
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Predictors of loss of hepatitis B surface antigen in HIV-infected patients | |
| AIM: To study factors associated with loss of hepatitis B surface antigen (HBsAg) in patients co-infected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV). METHODS: We retrospectively reviewed the medical records of 5681 patients follow | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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Clevudine for chronic hepatitis B: antiviral response, predictors of response, and development of myopathy | |
| Summary. Clevudine has been approved for the treatment of chronic hepatitis B (CHB) in South Korea. However, its long-term antiviral effect and safety awaits more study. The aim of this study was to evaluate antiviral efficacy, predictors of virologic res | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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Enhanced Liver Fibrosis (ELF) test accurately identifies liver fibrosis in patients with chronic hepatitis C | |
| Summary. Assessment of liver fibrosis is important in determining prognosis and evaluating interventions. Due to limitations of accuracy and patient hazard of liver biopsy, non-invasive methods have been sought to provide information on liver fibrosis, in | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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New trends of HCV infection in China revealed by genetic analysis of viral sequences determined from first-time volunteer blood donors | |
| Summary. Recently, we studied hepatitis C virus (HCV) sera-prevalence among 559 890 first-time volunteer blood donors in China. From randomly selected 450 anti-HCV positive donors, we detected HCV RNA in 270 donors. In this study, we amplified HCV E1 and/ | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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Pegylated interferon plus optimized weight-based ribavirin dosing negate the influence of weight and body mass index on early viral kinetics and sustained virological response in chronic hepatitis C | |
| Summary. Aim: Elevated body mass index (BMI) in chronic hepatitis C (CHC) has been associated with reduced rates of sustained virological response (SVR). The aims of this study were to determine whether early viral kinetics (and subsequently SVR) are infl | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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Diversity of Hepatitis B virus infecting Malaysian candidate blood donors is driven by viral and host factors | |
| Summary. Malaysia is a medium endemic country for hepatitis B virus (HBV) infection but little is known about HBV strains circulating in Malaysian blood donors. Viral load, HBsAg concentrations and nested PCR products from 84 HBV surface antigen (HBsAg) p | |||
| Mar 5, 2010 – SOURCE: Journal of Viral Hepatitis | |||
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Serum B12 levels predict response to treatment with interferon and ribavirin in patients with chronic HCV infection | |
| Summary. Vitamin B12 is stored in hepatocytes and inhibits hepatitis C virus (HCV) RNA translation. The implication of B12 in the setting of antiviral treatment is unknown. This study aims to retrospectively evaluate the discriminative efficacy of pretrea | |||
